Version 5.4
Bos taurus Gene: VAMP3
Summary
InnateDB Gene IDBG-633674.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VAMP3
Gene Name Vesicle-associated membrane protein 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014726
Encoded Proteins
IDBP-685396
Vesicle-associated membrane protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000049245:
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:46455183-46464710
Strand Reverse strand
Band
Transcripts
ENSBTAT00000019438 ENSBTAP00000019438
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001921 positive regulation of receptor recycling
GO:0006810 transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0017156 calcium ion-dependent exocytosis
GO:0034446 substrate adhesion-dependent cell spreading
GO:0035493 SNARE complex assembly
GO:0042147 retrograde transport, endosome to Golgi
GO:0043001 Golgi to plasma membrane protein transport
Cellular Component
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030136 clathrin-coated vesicle
GO:0030141 secretory granule
GO:0031410 cytoplasmic vesicle
GO:0043005 neuron projection
GO:0045202 synapse
GO:0055037 recycling endosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000049245
View Gene Order
ENSMUSG00000028955
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
hsa04145
Phagosome pathway
mmu04130
SNARE interactions in vesicular transport pathway
mmu04145
Phagosome pathway
INOH
PID NCI
arf6_traffickingpathway
Arf6 trafficking events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.1099
RefSeq NM_001045915
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca