Version 5.4
Bos taurus Gene: SMPD3
Summary
InnateDB Gene IDBG-634182.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMPD3
Gene Name sphingomyelin phosphodiesterase 3
Synonyms NSMase2
Species Bos taurus
Ensembl Gene ENSBTAG00000009639
Encoded Proteins
IDBP-685951
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103056:
Gene Information
Type Protein coding
Genomic Location Chromosome 18:35847645-35872312
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012702 ENSBTAP00000012702
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004767 sphingomyelin phosphodiesterase activity
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006684 sphingomyelin metabolic process
GO:0030072 peptide hormone secretion
Cellular Component
GO:0000137 Golgi cis cisterna
GO:0005794 Golgi apparatus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000103056
View Gene Order
ENSMUSG00000031906
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
REACT_116105
Glycosphingolipid metabolism pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_199008
Glycosphingolipid metabolism pathway
REACT_188937
Metabolism pathway
REACT_245163
Sphingolipid metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
mmu00600
Sphingolipid metabolism pathway
INOH
PID NCI
ceramide_pathway
Ceramide signaling pathway
Cross-References
SwissProt
TrEMBL E1BFH4
UniProt Splice Variant
Entrez Gene 514201
UniGene Bt.44886
RefSeq NM_001192363 XM_005218563 XM_005218564 XM_005218565 XM_005218566 XM_005218567 XM_005218568
HUGO HGNC:14240
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02046693
GenPept
RNA Seq Atlas 514201

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca