Version 5.4
Mus musculus Gene: Smpd3
Summary
InnateDB Gene IDBG-189852.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smpd3
Gene Name sphingomyelin phosphodiesterase 3, neutral
Synonyms 4631433G07Rik; AI427456; AW537966; fro; nSMase2
Species Mus musculus
Ensembl Gene ENSMUSG00000031906
Encoded Proteins
IDBP-189854
sphingomyelin phosphodiesterase 3, neutral
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103056:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:106252548-106337988
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000067512 ENSMUSP00000069255
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0046872 metal ion binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006684 sphingomyelin metabolic process
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0030072 peptide hormone secretion
Cellular Component
GO:0000137 Golgi cis cisterna
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000103056
View Gene Order
ENSBTAG00000009639
Not yet available
Pathways
NETPATH
REACTOME
REACT_199008
Glycosphingolipid metabolism pathway
REACT_188937
Metabolism pathway
REACT_245163
Sphingolipid metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
KEGG
mmu00600
Sphingolipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
REACT_116105
Glycosphingolipid metabolism pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
INOH
PID NCI
ceramide_pathway
Ceramide signaling pathway
Cross-References
SwissProt Q9JJY3
TrEMBL Q3US57
UniProt Splice Variant
Entrez Gene 58994
UniGene Mm.23298 Mm.487528
RefSeq NM_021491 XM_006531239 XM_006531240 XM_006531241
OMIM
CCDS CCDS22634
HPRD
IMGT
MGI ID MGI:1927578
MGI Symbol Smpd3
EMBL AJ250461 AK019476 AK139226 AK140788 BC043077 BC046980
GenPept AAH43077 AAH46980 BAB31745 BAE23925 BAE24479 CAB92970
RNA Seq Atlas 58994

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca