Version 5.4
Bos taurus Gene: INVS
Summary
InnateDB Gene IDBG-634200.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INVS
Gene Name inversin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009806
Encoded Proteins
IDBP-685969
inversin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119509:
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:65597445-65734342
Strand Forward strand
Band
Transcripts
ENSBTAT00000012932 ENSBTAP00000012932
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 82 interaction(s) predicted by orthology.
Predicted by orthology
Total 82 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001822 kidney development
GO:0009791 post-embryonic development
GO:0031016 pancreas development
GO:0048513 organ development
GO:0060971 embryonic heart tube left/right pattern formation
GO:0090090 negative regulation of canonical Wnt signaling pathway
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000119509
View Gene Order
ENSMUSG00000028344
View Gene Order
Cross-References
SwissProt
TrEMBL A0JN59
UniProt Splice Variant
Entrez Gene 529698
UniGene Bt.37551
RefSeq NM_001077983 XM_005210207
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126527 DAAA02023286
GenPept AAI26528
RNA Seq Atlas 529698

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca