Version 5.4
Bos taurus Gene: PUS10
Summary
InnateDB Gene IDBG-634280.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PUS10
Gene Name putative tRNA pseudouridine synthase Pus10
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009694
Encoded Proteins
IDBP-686061
pseudouridylate synthase 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162927:
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:43541231-43603979
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012785 ENSBTAP00000012785
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity
Biological Process
GO:0001522 pseudouridine synthesis
GO:0009451 RNA modification
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000162927
View Gene Order
ENSMUSG00000020280
View Gene Order
Cross-References
SwissProt
TrEMBL F1MRD5
UniProt Splice Variant
Entrez Gene 614986
UniGene Bt.57589
RefSeq NM_001206837 XM_005212677
HUGO HGNC:26505
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02031010 DAAA02031011 DAAA02031012 DAAA02031013 DAAA02031014 DAAA02031015 DAAA02031016 DAAA02031017
GenPept
RNA Seq Atlas 614986

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca