Mus musculus Gene: Pus10
Summary
InnateDB Gene IDBG-155506.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pus10
Gene Name pseudouridylate synthase 10
Synonyms 2810013G11Rik; 4933435A13Rik; AU014648; C77560; Ccdc139
Species Mus musculus
Ensembl Gene ENSMUSG00000020280
Encoded Proteins
pseudouridylate synthase 10
pseudouridylate synthase 10
pseudouridylate synthase 10
pseudouridylate synthase 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162927:
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:23665674-23732876
Strand Forward strand
Band A3.2
Transcripts
ENSMUST00000020520 ENSMUSP00000020520
ENSMUST00000058163 ENSMUSP00000050395
ENSMUST00000109525 ENSMUSP00000105151
ENSMUST00000136365
ENSMUST00000143117 ENSMUSP00000117934
ENSMUST00000139646
ENSMUST00000142287
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity
Biological Process
GO:0001522 pseudouridine synthesis
GO:0008033 tRNA processing
GO:0008150 biological_process
GO:0009451 RNA modification
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q9D3U0
TrEMBL B0QZU5
UniProt Splice Variant
Entrez Gene 74467
UniGene Mm.29536
RefSeq NM_001033654 NM_028304 NM_028956 XM_006514869
OMIM
CCDS CCDS24479
HPRD
IMGT
MGI ID MGI:1921717
MGI Symbol Pus10
EMBL AK012737 AK017063 AK028368 AK029866 AK088562 AK145055 AL672049 AL805916 BC025555 BX255874
GenPept AAH25555 BAB28439 BAB30576 BAC25908 BAC26650 BAC40426 BAE26208 CAI24204 CAI26149 CAM16949
RNA Seq Atlas 74467