Bos taurus Gene: SLC5A7 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-634457.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | SLC5A7 | ||||||||||||
Gene Name | high affinity choline transporter 1 | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000004352 | ||||||||||||
Encoded Proteins |
high affinity choline transporter 1
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115665:
Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).[supplied by OMIM, Mar 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 11:44876761-44897731 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Acetylcholine Neurotransmitter Release Cycle pathway
Transmembrane transport of small molecules pathway
Neuronal System pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Release Cycle pathway
SLC-mediated transmembrane transport pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
SLC-mediated transmembrane transport pathway
Acetylcholine Neurotransmitter Release Cycle pathway
Neurotransmitter Release Cycle pathway
Transmembrane transport of small molecules pathway
Neuronal System pathway
Transmission across Chemical Synapses pathway
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KEGG | |||||||||||||
INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | Q2KI26 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 512311 | ||||||||||||
UniGene | Bt.31731 | ||||||||||||
RefSeq | NM_001046116 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | BC112794 DAAA02031040 DAAA02031041 | ||||||||||||
GenPept | AAI12795 | ||||||||||||
RNA Seq Atlas | 512311 | ||||||||||||