Version 5.4
Bos taurus Gene: UXS1
Summary
InnateDB Gene IDBG-634480.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UXS1
Gene Name UDP-glucuronic acid decarboxylase 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005614
Encoded Proteins
IDBP-686326
UDP-glucuronate decarboxylase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115652:
This gene encodes an enyzme found in the perinuclear Golgi which catalyzes the synthesis of UDP-xylose used in glycosaminoglycan (GAG) synthesis on proteoglycans. The GAG chains are covalently attached to proteoglycans which participate in signaling pathways during development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:45583095-45639673
Strand Forward strand
Band
Transcripts
ENSBTAT00000007374 ENSBTAP00000007374
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042803 protein homodimerization activity
GO:0048040 UDP-glucuronate decarboxylase activity
GO:0050662 coenzyme binding
GO:0070403 NAD+ binding
Biological Process
GO:0006694 steroid biosynthetic process
GO:0044237 cellular metabolic process
GO:0051262 protein tetramerization
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000115652
View Gene Order
ENSMUSG00000057363
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00520
Amino sugar and nucleotide sugar metabolism pathway
hsa00500
Starch and sucrose metabolism pathway
mmu00520
Amino sugar and nucleotide sugar metabolism pathway
mmu00500
Starch and sucrose metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BMI4
UniProt Splice Variant
Entrez Gene 534788
UniGene Bt.57545
RefSeq NM_001206064 XM_005212786
HUGO HGNC:17729
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02031058 DAAA02031059 DAAA02031060
GenPept
RNA Seq Atlas 534788

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca