Bos taurus Gene: ARHGEF16
Summary
InnateDB Gene IDBG-634676.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGEF16
Gene Name rho guanine nucleotide exchange factor 16
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020837
Encoded Proteins
rho guanine nucleotide exchange factor 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130762:
Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:50811142-50834864
Strand Reverse strand
Band
Transcripts
ENSBTAT00000027769 ENSBTAP00000027769
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0017048 Rho GTPase binding
GO:0030165 PDZ domain binding
GO:0030971 receptor tyrosine kinase binding
Biological Process
GO:0032863 activation of Rac GTPase activity
GO:0032864 activation of Cdc42 GTPase activity
GO:0035023 regulation of Rho protein signal transduction
GO:0060326 cell chemotaxis
GO:0090004 positive regulation of establishment of protein localization to plasma membrane
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
NRAGE signals death through JNK pathway
G alpha (12/13) signalling events pathway
Rho GTPase cycle pathway
Signalling by NGF pathway
Signaling by Rho GTPases pathway
Signaling by GPCR pathway
p75 NTR receptor-mediated signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
NRAGE signals death through JNK pathway
Signaling by Rho GTPases pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
G alpha (12/13) signalling events pathway
Rho GTPase cycle pathway
Signalling by NGF pathway
Signal Transduction pathway
p75 NTR receptor-mediated signalling pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.108784 Bt.27352
RefSeq NM_001101998 XM_005217076 XM_005217077
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas