Version 5.4
Bos taurus Gene: SFRS9
Summary
InnateDB Gene IDBG-634794.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SFRS9
Gene Name serine/arginine-rich splicing factor 9
Synonyms SFRS9
Species Bos taurus
Ensembl Gene ENSBTAG00000012792
Encoded Proteins
IDBP-686576
splicing factor, arginine/serine-rich 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111786:
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two pseudogenes, one on chromosome 15 and the other on chromosome 21, have been found for this gene. [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:65008122-65014401
Strand Reverse strand
Band
Transcripts
ENSBTAT00000016997 ENSBTAP00000016997
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.
Predicted by orthology
Total 48 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0048025 negative regulation of mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000111786
View Gene Order
ENSMUSG00000029538
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1849
mRNA 3'-end processing pathway
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_1597
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_387
Cleavage of Growing Transcript in the Termination Region pathway
REACT_894
RNA Polymerase II Transcription Termination pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_1281
Transport of Mature Transcript to Cytoplasm pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
REACT_240247
mRNA 3'-end processing pathway
REACT_237682
Transport of Mature Transcript to Cytoplasm pathway
REACT_249110
mRNA Splicing pathway
REACT_257346
RNA Polymerase II Transcription Termination pathway
REACT_253727
Cleavage of Growing Transcript in the Termination Region pathway
REACT_233572
Gene Expression pathway
REACT_260226
mRNA Splicing - Major Pathway pathway
REACT_232353
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
REACT_233950
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_242255
RNA Polymerase II Transcription pathway
KEGG
hsa00970
Aminoacyl-tRNA biosynthesis pathway
hsa03040
Spliceosome pathway
mmu03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A4FUC6
UniProt Splice Variant
Entrez Gene 509905
UniGene Bt.30434 Bt.68603
RefSeq NM_001083398 XM_003585035 XM_005197541 XM_005203021
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114699 DAAA02045453
GenPept AAI14700
RNA Seq Atlas 100851440 101903900 509905

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca