Version 5.4
| Bos taurus Gene: DYNLL1 | |||||||||||||||||||||
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| Summary | |||||||||||||||||||||
| InnateDB Gene | IDBG-634795.3 | ||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
| Gene Symbol | DYNLL1 | ||||||||||||||||||||
| Gene Name | Dynein light chain 1, cytoplasmic | ||||||||||||||||||||
| Synonyms | |||||||||||||||||||||
| Species | Bos taurus | ||||||||||||||||||||
| Ensembl Gene | ENSBTAG00000024605 | ||||||||||||||||||||
| Encoded Proteins |
Dynein light chain 1, cytoplasmic
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088986:
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||
| Genomic Location | Chromosome 17:65042590-65045024 | ||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||
| Band | |||||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 128 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||||||||||||||
| NETPATH | |||||||||||||||||||||
| REACTOME |
G2/M Transition pathway
Activation of BIM and translocation to mitochondria pathway
Activation of BH3-only proteins pathway
Immune System pathway
Cell Cycle, Mitotic pathway
Loss of Nlp from mitotic centrosomes pathway
Mitotic G2-G2/M phases pathway
Cell Cycle pathway
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
MHC class II antigen presentation pathway
Intrinsic Pathway for Apoptosis pathway
Adaptive Immune System pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Centrosome maturation pathway
Apoptosis pathway
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| KEGG | |||||||||||||||||||||
| INOH | |||||||||||||||||||||
| PID NCI | |||||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
| NETPATH |
EGFR1 pathway
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| REACTOME |
Regulation of PLK1 Activity at G2/M Transition pathway
Loss of Nlp from mitotic centrosomes pathway
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
Recruitment of mitotic centrosome proteins and complexes pathway
MHC class II antigen presentation pathway
Activation of BIM and translocation to mitochondria pathway
Apoptosis pathway
Cell Cycle pathway
Adaptive Immune System pathway
Activation of BH3-only proteins pathway
Immune System pathway
Centrosome maturation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Intrinsic Pathway for Apoptosis pathway
Mitotic G2-G2/M phases pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Apoptosis pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of Nlp from mitotic centrosomes pathway
Cell Cycle pathway
Immune System pathway
Mitotic G2-G2/M phases pathway
MHC class II antigen presentation pathway
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Activation of BH3-only proteins pathway
Adaptive Immune System pathway
Activation of BIM and translocation to mitochondria pathway
Centrosome maturation pathway
Intrinsic Pathway for Apoptosis pathway
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| KEGG |
Vasopressin-regulated water reabsorption pathway
Vasopressin-regulated water reabsorption pathway
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| INOH | |||||||||||||||||||||
| PID NCI | |||||||||||||||||||||
| Cross-References | |||||||||||||||||||||
| SwissProt | P61285 | ||||||||||||||||||||
| TrEMBL | Q862K7 | ||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||
| Entrez Gene | 789121 | ||||||||||||||||||||
| UniGene | |||||||||||||||||||||
| RefSeq | NM_001003901 XM_005198126 XM_005198128 XM_005200198 XM_005201054 XM_005205926 | ||||||||||||||||||||
| HUGO | |||||||||||||||||||||
| OMIM | |||||||||||||||||||||
| CCDS | |||||||||||||||||||||
| HPRD | |||||||||||||||||||||
| IMGT | |||||||||||||||||||||
| EMBL | AB098977 AB099086 AY675078 BC102872 BT021030 | ||||||||||||||||||||
| GenPept | AAI02873 AAT84371 AAX09047 BAC56467 BAC56576 | ||||||||||||||||||||
| RNA Seq Atlas | 100336193 101908461 101909443 404151 789121 | ||||||||||||||||||||