InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.68753

Summary

InnateDB Gene

IDBG-634802.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.68753

Gene Name

tyrosine aminotransferase

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002214

Encoded Proteins

IDBP-686592

tyrosine aminotransferase

IDBP-686593

tyrosine aminotransferase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198650:
This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:39571695-39629597

Strand

Forward strand

Band

Transcripts

ENSBTAT00000046462	ENSBTAP00000043762
ENSBTAT00000002866	ENSBTAP00000002866

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004838	L-tyrosine:2-oxoglutarate aminotransferase activity
GO:0008483	transaminase activity
GO:0016829	lyase activity
GO:0030170	pyridoxal phosphate binding

Biological Process

GO:0006103	2-oxoglutarate metabolic process
GO:0006520	cellular amino acid metabolic process
GO:0006536	glutamate metabolic process
GO:0006572	tyrosine catabolic process
GO:0008152	metabolic process
GO:0009058	biosynthetic process
GO:0009072	aromatic amino acid family metabolic process
GO:0009074	aromatic amino acid family catabolic process