Version 5.4
Bos taurus Gene: NUBP2
Summary
InnateDB Gene IDBG-634831.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUBP2
Gene Name Cytosolic Fe-S cluster assembly factor NUBP2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016561
Encoded Proteins
IDBP-686626
Cytosolic Fe-S cluster assembly factor NUBP2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000095906:
NUBP2 is a member of the NUBP/MRP gene subfamily of ATP-binding proteins (see NUBP1; MIM 600280) (Nakashima et al., 1999 [PubMed 10486206]).[supplied by OMIM, Mar 2008]
This gene encodes an adenosine triphosphate (ATP) and metal-binding protein that is required for the assembly of cyotosolic iron-sulfur proteins. The encoded protein functions in a heterotetramer with nucleotide-binding protein 1 (NUBP1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:1360579-1365802
Strand Forward strand
Band
Transcripts
ENSBTAT00000022029 ENSBTAP00000022029
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0016226 iron-sulfur cluster assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005856 cytoskeleton
GO:0031616 spindle pole centrosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000095906
View Gene Order
ENSMUSG00000039183
View Gene Order
Pathways
NETPATH
REACTOME
REACT_211577
Cytosolic iron-sulfur cluster assembly pathway
REACT_219139
Metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160176
Cytosolic iron-sulfur cluster assembly pathway
REACT_111217
Metabolism pathway
REACT_188937
Metabolism pathway
REACT_196637
Cytosolic iron-sulfur cluster assembly pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q3MHY6
TrEMBL M5FK02
UniProt Splice Variant
Entrez Gene 515660
UniGene Bt.2198
RefSeq NM_001034505
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC104526 GJ062847
GenPept AAI04527 DAA15585
RNA Seq Atlas 515660

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca