Homo sapiens Gene: NUBP2
Summary
InnateDB Gene IDBG-9320.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUBP2
Gene Name nucleotide binding protein 2
Synonyms CFD1; NBP 2; NUBP1
Species Homo sapiens
Ensembl Gene ENSG00000095906
Encoded Proteins
nucleotide binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary NUBP2 is a member of the NUBP/MRP gene subfamily of ATP-binding proteins (see NUBP1; MIM 600280) (Nakashima et al., 1999 [PubMed 10486206]).[supplied by OMIM, Mar 2008]
This gene encodes an adenosine triphosphate (ATP) and metal-binding protein that is required for the assembly of cyotosolic iron-sulfur proteins. The encoded protein functions in a heterotetramer with nucleotide-binding protein 1 (NUBP1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:1782901-1789191
Strand Forward strand
Band p13.3
Transcripts
ENST00000262302 ENSP00000262302
ENST00000565987 ENSP00000455896
ENST00000568610
ENST00000568834 ENSP00000456928
ENST00000568706 ENSP00000460079
ENST00000565134 ENSP00000454815
ENST00000566090
ENST00000566447
ENST00000563136 ENSP00000454576
ENST00000567700
ENST00000565603
ENST00000569898 ENSP00000456284
ENST00000562263 ENSP00000456199
ENST00000564227 ENSP00000455739
ENST00000568287 ENSP00000454982
ENST00000563821
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 45 experimentally validated interaction(s) in this database.
Experimentally validated
Total 45 [view]
Protein-Protein 45 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0016226 iron-sulfur cluster assembly
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031616 spindle pole centrosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Cytosolic iron-sulfur cluster assembly pathway
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.256549
RefSeq NM_001284501 NM_001284502 NM_012225 XM_005255025 XM_005255027 XM_005255028 XM_005255030
HUGO
OMIM
CCDS CCDS10445 CCDS66898
HPRD 14846
IMGT
EMBL
GenPept
RNA Seq Atlas