InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: TRPC5

Summary

InnateDB Gene

IDBG-634841.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRPC5

Gene Name

Short transient receptor potential channel 5

Synonyms

trp

Species

Bos taurus

Ensembl Gene

ENSBTAG00000010065

Encoded Proteins

IDBP-686634

Short transient receptor potential channel 5

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072315:
This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). [provided by RefSeq, May 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:65246771-65449919

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000013270

ENSBTAP00000013270

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005262	calcium channel activity
GO:0005515	protein binding
GO:0070679	inositol 1,4,5 trisphosphate binding

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006816	calcium ion transport
GO:0055085	transmembrane transport
GO:0070588	calcium ion transmembrane transport