InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: EHHADH

Summary

InnateDB Gene

IDBG-634843.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EHHADH

Gene Name

peroxisomal bifunctional enzyme

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000019625

Encoded Proteins

IDBP-686641

peroxisomal bifunctional enzyme

IDBP-686642

peroxisomal bifunctional enzyme

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113790:
The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:82467817-82521151

Strand

Forward strand

Band

Transcripts

ENSBTAT00000061513	ENSBTAP00000053200
ENSBTAT00000036047	ENSBTAP00000035911

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
GO:0005102	receptor binding
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0019899	enzyme binding
GO:0050662	coenzyme binding

Biological Process

GO:0006475	internal protein amino acid acetylation
GO:0006631	fatty acid metabolic process
GO:0008152	metabolic process
GO:0055114	oxidation-reduction process