Bos taurus Gene: WNT2B | |||||||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||||||
InnateDB Gene | IDBG-635013.3 | ||||||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||||||
Gene Symbol | WNT2B | ||||||||||||||||||||||||||||
Gene Name | protein Wnt-2b | ||||||||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||||||||||
Ensembl Gene | ENSBTAG00000014291 | ||||||||||||||||||||||||||||
Encoded Proteins |
protein Wnt-2b
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Protein Structure | |||||||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||||||
InnateDB Annotation from Orthologs | |||||||||||||||||||||||||||||
Summary |
[Homo sapiens] Secretion of WNT2B upon virus infection negatively regulates antiviral innate immunity.
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Entrez Gene | |||||||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134245:
This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternatively spliced transcript variants. [provided by RefSeq, Aug 2008] This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
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Gene Information | |||||||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||||||
Genomic Location | Chromosome 3:30942961-30957520 | ||||||||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||||||||
Band | |||||||||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||||||
REACTOME |
Class B/2 (Secretin family receptors) pathway
Signaling by WNT in cancer pathway
Signaling by Wnt pathway
Signaling by GPCR pathway
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 pathway
Signal Transduction pathway
WNT ligand biogenesis and trafficking pathway
GPCR ligand binding pathway
Disease pathway
Disease pathway
Signaling by Wnt pathway
WNT ligand biogenesis and trafficking pathway
Signaling by WNT in cancer pathway
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 pathway
Signal Transduction pathway
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KEGG |
Wnt signaling pathway pathway
Hedgehog signaling pathway pathway
Basal cell carcinoma pathway
Melanogenesis pathway
Pathways in cancer pathway
Basal cell carcinoma pathway
Melanogenesis pathway
Wnt signaling pathway pathway
Hedgehog signaling pathway pathway
Pathways in cancer pathway
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INOH |
Wnt signaling pathway pathway
GPCR signaling pathway
Wnt signaling pathway pathway
GPCR signaling pathway
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PID NCI | |||||||||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||||||
UniGene | Bt.27254 | ||||||||||||||||||||||||||||
RefSeq | NM_001099363 | ||||||||||||||||||||||||||||
HUGO | |||||||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||||||
CCDS | |||||||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||||||
EMBL | |||||||||||||||||||||||||||||
GenPept | |||||||||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||||||||