InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CCT4

Summary

InnateDB Gene

IDBG-635426.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CCT4

Gene Name

T-complex protein 1 subunit delta

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004531

Encoded Proteins

IDBP-687264

T-complex protein 1 subunit delta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115484:
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:60397422-60410035

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000044819

ENSBTAP00000042274

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 79 interaction(s) predicted by orthology.

Predicted by orthology
Total	79 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0044822	poly(A) RNA binding
GO:0051082	unfolded protein binding

Biological Process

GO:0006457	protein folding
GO:0007339	binding of sperm to zona pellucida
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0002199	zona pellucida receptor complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005832	chaperonin-containing T-complex
GO:0005874	microtubule
GO:0044297	cell body
GO:0070062	extracellular vesicular exosome