Version 5.4
| Bos taurus Gene: PPP2R2A | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Gene | IDBG-635620.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PPP2R2A | ||||||||
| Gene Name | serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000018317 | ||||||||
| Encoded Proteins |
protein phosphatase 2, regulatory subunit B, alpha
|
||||||||
| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000221914:
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010] |
||||||||
| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 8:74834628-74913332 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
|
||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Orthologs | |||||||||
|
Species
Mus musculus
Homo sapiens
|
Gene ID
Gene Order
|
||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
TGF_beta_Receptor pathway
|
||||||||
| REACTOME |
G2/M Transition pathway
Cell Cycle, Mitotic pathway
G1 Phase pathway
Nuclear Envelope Reassembly pathway
Cell Cycle pathway
Nonsense-Mediated Decay (NMD) pathway
M Phase pathway
Cyclin D associated events in G1 pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Mitotic G2-G2/M phases pathway
Mitotic Metaphase and Anaphase pathway
Cyclin A/B1 associated events during G2/M transition pathway
Mitotic G1-G1/S phases pathway
Gene Expression pathway
Initiation of Nuclear Envelope Reformation pathway
Mitotic Anaphase pathway
Initiation of Nuclear Envelope Reformation pathway
Cyclin D associated events in G1 pathway
Cyclin A/B1 associated events during G2/M transition pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
G1 Phase pathway
Nonsense-Mediated Decay (NMD) pathway
Mitotic G1-G1/S phases pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
G2/M Transition pathway
Nuclear Envelope Reassembly pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Gene Expression pathway
Mitotic Metaphase and Anaphase pathway
|
||||||||
| KEGG |
Tight junction pathway
mRNA surveillance pathway pathway
Hepatitis C pathway
Chagas disease (American trypanosomiasis) pathway
Tight junction pathway
Chagas disease (American trypanosomiasis) pathway
mRNA surveillance pathway pathway
Hepatitis C pathway
|
||||||||
| INOH | |||||||||
| PID NCI |
ErbB1 downstream signaling
TGF-beta receptor signaling
|
||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F1MG56 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 508045 | ||||||||
| UniGene | Bt.30324 | ||||||||
| RefSeq | NM_001191533 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02023817 DAAA02023818 DAAA02023819 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 508045 | ||||||||