Bos taurus Gene: PFAS
Summary
InnateDB Gene IDBG-635737.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PFAS
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000031509
Encoded Proteins
phosphoribosylformylglycinamidine synthase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178921:
Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:28498629-28511705
Strand Forward strand
Band
Transcripts
ENSBTAT00000044654 ENSBTAP00000042131
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004642 phosphoribosylformylglycinamidine synthase activity
GO:0016874 ligase activity
Biological Process
GO:0006189 'de novo' IMP biosynthetic process
GO:0008152 metabolic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Purine ribonucleoside monophosphate biosynthesis pathway
Metabolism of nucleotides pathway
Purine metabolism pathway
Metabolism pathway
Purine metabolism pathway
Metabolism pathway
Purine ribonucleoside monophosphate biosynthesis pathway
Metabolism of nucleotides pathway
KEGG
Purine metabolism pathway
Purine metabolism pathway
INOH
Purine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1N4K1 Q6PWM4
UniProt Splice Variant
Entrez Gene 520318
UniGene Bt.63778
RefSeq NM_001256564 XM_005220359 XM_005220360
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY573607 DAAA02048815
GenPept AAS86199
RNA Seq Atlas 520318