Bos taurus Gene: AQP3 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-635798.3 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | AQP3 | ||||||||||||||
Gene Name | Aquaporin-3 | ||||||||||||||
Synonyms | |||||||||||||||
Species | Bos taurus | ||||||||||||||
Ensembl Gene | ENSBTAG00000008493 | ||||||||||||||
Encoded Proteins |
Aquaporin-3
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
InnateDB Annotation from Orthologs | |||||||||||||||
Summary |
[Homo sapiens] AQP3 is an aquaporin that functions in macrophage immunity by a cellular mechanism involving facilitated water and glycerol transport, and consequent phagocytic and migration activity. AQP3, therefore, is a novel therapeutic target in modulating the innate immune response in various infectious and inflammatory conditions.
[Mus musculus] Aqp3 is an aquaporin that functions in macrophage immunity by a cellular mechanism involving facilitated water and glycerol transport, and consequent phagocytic and migration activity. Aqp3, therefore, is a novel therapeutic target in modulating the innate immune response in various infectious and inflammatory conditions.
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Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165272:
This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. [provided by RefSeq, Aug 2011] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 8:76525369-76531334 | ||||||||||||||
Strand | Reverse strand | ||||||||||||||
Band | |||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Aquaporin-mediated transport pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
Transmembrane transport of small molecules pathway
Passive transport by Aquaporins pathway
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KEGG | |||||||||||||||
INOH | |||||||||||||||
PID NCI | |||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Passive transport by Aquaporins pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
Transmembrane transport of small molecules pathway
Aquaporin-mediated transport pathway
Aquaporin-mediated transport pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
Passive transport by Aquaporins pathway
Transmembrane transport of small molecules pathway
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KEGG |
Vasopressin-regulated water reabsorption pathway
Vasopressin-regulated water reabsorption pathway
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INOH | |||||||||||||||
PID NCI |
Stabilization and expansion of the E-cadherin adherens junction
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Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | |||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | |||||||||||||||
UniGene | Bt.53350 | ||||||||||||||
RefSeq | NM_001079794 | ||||||||||||||
HUGO | |||||||||||||||
OMIM | |||||||||||||||
CCDS | |||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | |||||||||||||||
GenPept | |||||||||||||||
RNA Seq Atlas | |||||||||||||||