Bos taurus Gene: BT.105130
Summary
InnateDB Gene IDBG-635810.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.105130
Gene Name ubiquitin-conjugating enzyme E2 R2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000693
Encoded Proteins
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107341:
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:76567996-76663653
Strand Forward strand
Band
Transcripts
ENSBTAT00000000925 ENSBTAP00000000925
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0006513 protein monoubiquitination
GO:0070936 protein K48-linked ubiquitination
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
KEGG
Ubiquitin mediated proteolysis pathway
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BAB9
UniProt Splice Variant
Entrez Gene 537885
UniGene Bt.105130
RefSeq NM_001206110
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02023865 DAAA02023866 DAAA02023867 DAAA02023868
GenPept
RNA Seq Atlas 537885