Version 5.4
| Bos taurus Gene: THBS2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-636041.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | THBS2 | ||||||||
| Gene Name | thrombospondin-2 precursor | ||||||||
| Synonyms | TMEM200A; TSP-2 | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000018810 | ||||||||
| Encoded Proteins |
thrombospondin-2 precursor
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186340:
The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 9:104735657-104760261 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Signaling by PDGF pathway
Post-translational protein modification pathway
Signal Transduction pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
Signaling by PDGF pathway
Signal Transduction pathway
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| KEGG |
ECM-receptor interaction pathway
Focal adhesion pathway
Malaria pathway
Phagosome pathway
ECM-receptor interaction pathway
Focal adhesion pathway
Malaria pathway
Phagosome pathway
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| INOH | |||||||||
| PID NCI |
Beta1 integrin cell surface interactions
Alpha4 beta1 integrin signaling events
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F1N1W3 Q28195 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 338092 | ||||||||
| UniGene | Bt.5522 | ||||||||
| RefSeq | NM_176872 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02027559 X89512 | ||||||||
| GenPept | CAA61683 | ||||||||
| RNA Seq Atlas | 338092 | ||||||||