Version 5.4
| Bos taurus Gene: TBL1XR1 | |||||||||||||||||
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| Summary | |||||||||||||||||
| InnateDB Gene | IDBG-636106.3 | ||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
| Gene Symbol | TBL1XR1 | ||||||||||||||||
| Gene Name | F-box-like/WD repeat-containing protein TBL1XR1 | ||||||||||||||||
| Synonyms | |||||||||||||||||
| Species | Bos taurus | ||||||||||||||||
| Ensembl Gene | ENSBTAG00000021910 | ||||||||||||||||
| Encoded Proteins |
transducin (beta)-like 1 X-linked receptor 1
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| Protein Structure | |||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
| Entrez Gene | |||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177565:
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||
| Type | Protein coding | ||||||||||||||||
| Genomic Location | Chromosome 1:90517079-90605473 | ||||||||||||||||
| Strand | Forward strand | ||||||||||||||||
| Band | |||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||
| NETPATH | |||||||||||||||||
| REACTOME |
NOTCH1 Intracellular Domain Regulates Transcription pathway
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
RORA activates circadian gene expression pathway
BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway
REV-ERBA represses gene expression pathway
Circadian Clock pathway
Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
Generic Transcription Pathway pathway
Transcriptional regulation of white adipocyte differentiation pathway
Transmembrane transport of small molecules pathway
Organelle biogenesis and maintenance pathway
Developmental Biology pathway
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
Metabolism of lipids and lipoproteins pathway
Signaling by NOTCH1 in Cancer pathway
Mitochondrial biogenesis pathway
FBXW7 Mutants and NOTCH1 in Cancer pathway
Signal Transduction pathway
Orphan transporters pathway
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
HDACs deacetylate histones pathway
Transcriptional activation of mitochondrial biogenesis pathway
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
Chromatin organization pathway
Signaling by NOTCH pathway
Chromatin modifying enzymes pathway
Signaling by NOTCH1 pathway
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
Metabolism pathway
Gene Expression pathway
Disease pathway
Rora activates circadian gene expression pathway
Circadian Clock pathway
Transcriptional regulation of white adipocyte differentiation pathway
Organelle biogenesis and maintenance pathway
Mus musculus biological processes pathway
Chromatin organization pathway
Disease pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Circadian Clock pathway
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
REV-ERBA represses gene expression pathway
RORA activates circadian gene expression pathway
Orphan transporters pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Chromatin modifying enzymes pathway
Signaling by NOTCH1 pathway
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
Signaling by NOTCH1 in Cancer pathway
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
FBXW7 Mutants and NOTCH1 in Cancer pathway
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
Transcriptional activation of mitochondrial biogenesis pathway
Transmembrane transport of small molecules pathway
Gene Expression pathway
PPARA activates gene expression pathway
Developmental Biology pathway
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
NOTCH1 Intracellular Domain Regulates Transcription pathway
Generic Transcription Pathway pathway
Signal Transduction pathway
Mitochondrial biogenesis pathway
HDACs deacetylate histones pathway
Signaling by NOTCH pathway
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway
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| KEGG |
Wnt signaling pathway pathway
Wnt signaling pathway pathway
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| INOH | |||||||||||||||||
| PID NCI |
Regulation of nuclear beta catenin signaling and target gene transcription
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| Cross-References | |||||||||||||||||
| SwissProt | |||||||||||||||||
| TrEMBL | |||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||
| Entrez Gene | |||||||||||||||||
| UniGene | Bt.25104 | ||||||||||||||||
| RefSeq | NM_001193029 XM_005201666 XM_005201667 | ||||||||||||||||
| HUGO | |||||||||||||||||
| OMIM | |||||||||||||||||
| CCDS | |||||||||||||||||
| HPRD | |||||||||||||||||
| IMGT | |||||||||||||||||
| EMBL | |||||||||||||||||
| GenPept | |||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||