Version 5.4
Bos taurus Gene: EFNB1
Summary
InnateDB Gene IDBG-636377.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EFNB1
Gene Name ephrin-B1 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015801
Encoded Proteins
IDBP-688294
ephrin-B1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090776:
The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:86944028-86956186
Strand Reverse strand
Band
Transcripts
ENSBTAT00000020985 ENSBTAP00000020985
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046875 ephrin receptor binding
Biological Process
GO:0001755 neural crest cell migration
GO:0007411 axon guidance
GO:0009880 embryonic pattern specification
GO:0042102 positive regulation of T cell proliferation
GO:0048013 ephrin receptor signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0045121 membrane raft
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000090776
View Gene Order
ENSMUSG00000031217
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_111045
Developmental Biology pathway
REACT_228085
EPHB-mediated forward signaling pathway
REACT_18266
Axon guidance pathway
REACT_228226
Ephrin signaling pathway
REACT_228189
EPH-ephrin mediated repulsion of cells pathway
REACT_228170
EPH-Ephrin signaling pathway
REACT_243590
EPH-ephrin mediated repulsion of cells pathway
REACT_258158
EPH-Ephrin signaling pathway
REACT_257656
EPHB-mediated forward signaling pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
REACT_241951
Ephrin signaling pathway
KEGG
hsa04360
Axon guidance pathway
mmu04360
Axon guidance pathway
INOH
PID NCI
ephbfwdpathway
EPHB forward signaling
ephrinbrevpathway
Ephrin B reverse signaling
ephrinb_ephbpathway
EphrinB-EPHB pathway
Cross-References
SwissProt
TrEMBL A1L570
UniProt Splice Variant
Entrez Gene 534413
UniGene Bt.56346
RefSeq NM_001080299
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT029857 DAAA02072909
GenPept ABM21555
RNA Seq Atlas 534413

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca