InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Efnb1

Summary

InnateDB Gene

IDBG-161815.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Efnb1

Gene Name

ephrin B1

Synonyms

Cek5-L; EFL-3; Elk-L; Epl2; Eplg2; LERK-2; Lerk2; Stra1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031217

Encoded Proteins

IDBP-161817

ephrin B1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090776:
The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:99136130-99148991

Strand

Forward strand

Band

Transcripts

ENSMUST00000052839	ENSMUSP00000050716
ENSMUST00000151750

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0046875	ephrin receptor binding

Biological Process

GO:0001755	neural crest cell migration
GO:0007411	axon guidance
GO:0009880	embryonic pattern specification
GO:0042102	positive regulation of T cell proliferation
GO:0048013	ephrin receptor signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0045121	membrane raft
GO:0070062	extracellular vesicular exosome