Bos taurus Gene: SNAP25 | |||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||
InnateDB Gene | IDBG-636453.3 | ||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||
Gene Symbol | SNAP25 | ||||||||||||||||||||||||
Gene Name | Synaptosomal-associated protein 25 | ||||||||||||||||||||||||
Synonyms | SNAP-25 | ||||||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||||||
Ensembl Gene | ENSBTAG00000008323 | ||||||||||||||||||||||||
Encoded Proteins |
Synaptosomal-associated protein 25
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Protein Structure | |||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132639:
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||
Genomic Location | Chromosome 13:3369182-3452555 | ||||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||||
Band | |||||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||
REACTOME |
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Metabolism pathway
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KEGG | |||||||||||||||||||||||||
INOH | |||||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||
REACTOME |
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Neurotoxicity of clostridium toxins pathway
Dopamine Neurotransmitter Release Cycle pathway
Acetylcholine Neurotransmitter Release Cycle pathway
Serotonin Neurotransmitter Release Cycle pathway
Glutamate Neurotransmitter Release Cycle pathway
GABA synthesis, release, reuptake and degradation pathway
Norepinephrine Neurotransmitter Release Cycle pathway
Toxicity of botulinum toxin type A (BoNT/A) pathway
Neuronal System pathway
Uptake and actions of bacterial toxins pathway
Transmission across Chemical Synapses pathway
Toxicity of botulinum toxin type E (BoNT/E) pathway
Neurotransmitter Release Cycle pathway
Metabolism pathway
Disease pathway
Toxicity of botulinum toxin type C (BoNT/C) pathway
Integration of energy metabolism pathway
GABA synthesis, release, reuptake and degradation pathway
Acetylcholine Neurotransmitter Release Cycle pathway
Metabolism pathway
Regulation of insulin secretion pathway
Neurotransmitter Release Cycle pathway
Norepinephrine Neurotransmitter Release Cycle pathway
Neuronal System pathway
Glutamate Neurotransmitter Release Cycle pathway
Transmission across Chemical Synapses pathway
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KEGG | |||||||||||||||||||||||||
INOH | |||||||||||||||||||||||||
PID NCI |
Effects of Botulinum toxin
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Cross-References | |||||||||||||||||||||||||
SwissProt | Q17QQ3 | ||||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||
Entrez Gene | 540853 | ||||||||||||||||||||||||
UniGene | Bt.42529 | ||||||||||||||||||||||||
RefSeq | NM_001076246 XM_005214074 | ||||||||||||||||||||||||
HUGO | |||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||
CCDS | |||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||
EMBL | BC118237 | ||||||||||||||||||||||||
GenPept | AAI18238 | ||||||||||||||||||||||||
RNA Seq Atlas | 540853 | ||||||||||||||||||||||||