Bos taurus Gene: SSR1
Summary
InnateDB Gene IDBG-636502.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SSR1
Gene Name Translocon-associated protein subunit alpha
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000022731
Encoded Proteins
Translocon-associated protein subunit alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124783:
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. [provided by RefSeq, Jul 2008]
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:47853793-47871932
Strand Forward strand
Band
Transcripts
ENSBTAT00000008253 ENSBTAP00000008253
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
SRP-dependent cotranslational protein targeting to membrane pathway
Gene Expression pathway
Translation pathway
IRE1alpha activates chaperones pathway
Metabolism of proteins pathway
XBP1(S) activates chaperone genes pathway
Unfolded Protein Response (UPR) pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
XBP1(S) activates chaperone genes pathway
IRE1alpha activates chaperones pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Unfolded Protein Response (UPR) pathway
Translation pathway
Metabolism of proteins pathway
Gene Expression pathway
Unfolded Protein Response (UPR) pathway
Translation pathway
Metabolism of proteins pathway
IRE1alpha activates chaperones pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Gene Expression pathway
XBP1(S) activates chaperone genes pathway
KEGG
Protein processing in endoplasmic reticulum pathway
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.13194 Bt.85320
RefSeq NM_001102122 XM_005223870
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas