Version 5.4
Bos taurus Gene: TASP1
Summary
InnateDB Gene IDBG-636534.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TASP1
Gene Name threonine aspartase 1
Synonyms C20orf13
Species Bos taurus
Ensembl Gene ENSBTAG00000021614
Encoded Proteins
IDBP-688465
threonine aspartase 1
IDBP-688475
threonine aspartase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089123:
This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:7131227-7383858
Strand Reverse strand
Band
Transcripts
ENSBTAT00000039537 ENSBTAP00000039328
ENSBTAT00000028803 ENSBTAP00000028803
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004298 threonine-type endopeptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000089123
View Gene Order
ENSMUSG00000039033
View Gene Order
Cross-References
SwissProt
TrEMBL Q0VD17
UniProt Splice Variant
Entrez Gene 532606
UniGene Bt.44002
RefSeq NM_001034577 XM_005214071
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC119884 DAAA02035133 DAAA02035134 DAAA02035135 DAAA02035136 DAAA02035137 DAAA02035138 DAAA02035139
GenPept AAI19885
RNA Seq Atlas 532606

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca