Version 5.4
Bos taurus Gene: MTF2
Summary
InnateDB Gene IDBG-636540.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTF2
Gene Name metal-response element-binding transcription factor 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001393
Encoded Proteins
IDBP-688468
metal-response element-binding transcription factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143033:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:50490450-50560463
Strand Reverse strand
Band
Transcripts
ENSBTAT00000001831 ENSBTAP00000001831
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0035064 methylated histone binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0007379 segment specification
GO:0019827 stem cell maintenance
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048863 stem cell differentiation
GO:0061086 negative regulation of histone H3-K27 methylation
GO:0061087 positive regulation of histone H3-K27 methylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0035098 ESC/E(Z) complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000143033
View Gene Order
ENSMUSG00000029267
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200808
PRC2 methylates histones and DNA pathway
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_71
Gene Expression pathway
REACT_222475
PRC2 methylates histones and DNA pathway
REACT_205737
Epigenetic regulation of gene expression pathway
REACT_233572
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.89091
RefSeq NM_001046556 XM_005204312 XM_005204313
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca