Version 5.4
Mus musculus Gene: Mtf2
Summary
InnateDB Gene IDBG-187572.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtf2
Gene Name metal response element binding transcription factor 2
Synonyms 9230112N11Rik; AA537621; C76717; M96; Pcl2
Species Mus musculus
Ensembl Gene ENSMUSG00000029267
Encoded Proteins
IDBP-187574
metal response element binding transcription factor 2
IDBP-255604
metal response element binding transcription factor 2
IDBP-627406
metal response element binding transcription factor 2
IDBP-627413
metal response element binding transcription factor 2
IDBP-627417
metal response element binding transcription factor 2
IDBP-538186
metal response element binding transcription factor 2
IDBP-724804
IDBP-627407
metal response element binding transcription factor 2
IDBP-627425
metal response element binding transcription factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143033:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:108065674-108109004
Strand Forward strand
Band F
Transcripts
ENSMUST00000081567 ENSMUSP00000080278
ENSMUST00000112626 ENSMUSP00000108245
ENSMUST00000131291
ENSMUST00000124195 ENSMUSP00000126297
ENSMUST00000131264
ENSMUST00000141592
ENSMUST00000134026 ENSMUSP00000128797
ENSMUST00000143412 ENSMUSP00000132596
ENSMUST00000137996 ENSMUSP00000121697
ENSMUST00000129921 ENSMUSP00000137843
ENSMUST00000172045 ENSMUSP00000126452
ENSMUST00000170319 ENSMUSP00000130536
ENSMUST00000163823
ENSMUST00000163195
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0035064 methylated histone binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0007379 segment specification
GO:0016568 chromatin modification
GO:0019827 stem cell maintenance
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048863 stem cell differentiation
GO:0061086 negative regulation of histone H3-K27 methylation
GO:0061087 positive regulation of histone H3-K27 methylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0035098 ESC/E(Z) complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143033
View Gene Order
ENSBTAG00000001393
Not yet available
Pathways
NETPATH
REACTOME
REACT_222475
PRC2 methylates histones and DNA pathway
REACT_205737
Epigenetic regulation of gene expression pathway
REACT_233572
Gene Expression pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200808
PRC2 methylates histones and DNA pathway
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.257149 Mm.448552
RefSeq NM_001253877 NM_001253878 NM_001253879 NM_001253880 NM_013827 XM_006534808 XM_006534809 XM_006534810 XM_006534811 XM_006534812 XM_006534813
OMIM
CCDS CCDS39201
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca