Version 5.4
Bos taurus Gene: PECI
Summary
InnateDB Gene IDBG-636573.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PECI
Gene Name enoyl-CoA delta isomerase 2, mitochondrial
Synonyms PECI
Species Bos taurus
Ensembl Gene ENSBTAG00000015178
Encoded Proteins
IDBP-688507
peroxisomal 3,2-trans-enoyl-CoA isomerase
IDBP-688510
peroxisomal 3,2-trans-enoyl-CoA isomerase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198721:
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:49907476-49923551
Strand Forward strand
Band
Transcripts
ENSBTAT00000020196 ENSBTAP00000020196
ENSBTAT00000039110 ENSBTAP00000038911
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000062 fatty-acyl-CoA binding
GO:0003824 catalytic activity
GO:0005102 receptor binding
GO:0016853 isomerase activity
Biological Process
GO:0008152 metabolic process
GO:0009062 fatty acid catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000198721
View Gene Order
ENSMUSG00000021417
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00071
Fatty acid degradation pathway
hsa04146
Peroxisome pathway
mmu00071
Fatty acid degradation pathway
mmu04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MWY9
UniProt Splice Variant
Entrez Gene 505355
UniGene Bt.47386
RefSeq NM_001034242
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02055879
GenPept
RNA Seq Atlas 505355

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca