Version 5.4
Mus musculus Gene: Eci2
Summary
InnateDB Gene IDBG-144727.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eci2
Gene Name enoyl-Coenzyme A delta isomerase 2
Synonyms Acbd2; Drs1; Hca88; Peci
Species Mus musculus
Ensembl Gene ENSMUSG00000021417
Encoded Proteins
IDBP-144729
enoyl-Coenzyme A delta isomerase 2
IDBP-260678
enoyl-Coenzyme A delta isomerase 2
IDBP-620094
enoyl-Coenzyme A delta isomerase 2
IDBP-620096
enoyl-Coenzyme A delta isomerase 2
IDBP-620097
enoyl-Coenzyme A delta isomerase 2
IDBP-620098
enoyl-Coenzyme A delta isomerase 2
IDBP-620099
enoyl-Coenzyme A delta isomerase 2
IDBP-620100
enoyl-Coenzyme A delta isomerase 2
IDBP-620101
enoyl-Coenzyme A delta isomerase 2
IDBP-714017
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198721:
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:34977748-35027094
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000021854 ENSMUSP00000021854
ENSMUST00000084345
ENSMUST00000110251 ENSMUSP00000105880
ENSMUST00000171229 ENSMUSP00000131735
ENSMUST00000166109
ENSMUST00000164421
ENSMUST00000170538 ENSMUSP00000129428
ENSMUST00000163280 ENSMUSP00000126500
ENSMUST00000170989 ENSMUSP00000129477
ENSMUST00000167036 ENSMUSP00000130076
ENSMUST00000171258 ENSMUSP00000129164
ENSMUST00000169759 ENSMUSP00000130283
ENSMUST00000178421 ENSMUSP00000137411
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000062 fatty-acyl-CoA binding
GO:0003824 catalytic activity
GO:0004165 dodecenoyl-CoA delta-isomerase activity
GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds
Biological Process
GO:0006635 fatty acid beta-oxidation
GO:0008152 metabolic process
GO:0009062 fatty acid catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198721
View Gene Order
ENSBTAG00000015178
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00071
Fatty acid degradation pathway
mmu04146
Peroxisome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00071
Fatty acid degradation pathway
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.28883
RefSeq NM_001110331 NM_001110332 NM_011868 XM_006516673 XM_006516674 XM_006516675 XM_006516676 XM_006516677
OMIM
CCDS CCDS26450 CCDS49234
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca