InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: TAF3

Summary

InnateDB Gene

IDBG-636873.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TAF3

Gene Name

Uncharacterized protein

Synonyms

TAF3

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002836

Encoded Proteins

IDBP-688851

TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165632:
The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]).[supplied by OMIM, May 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:16043506-16163986

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000003674

ENSBTAP00000003674

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002039	p53 binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0051457	maintenance of protein location in nucleus