InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.91663

Summary

InnateDB Gene

IDBG-636914.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.91663

Gene Name

myosin-2

Synonyms

MyHC-2a

Species

Bos taurus

Ensembl Gene

ENSBTAG00000007090

Encoded Proteins

IDBP-688928

myosin-2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125414:
Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:30137767-30165109

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000012797

ENSBTAP00000012797

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003735	structural constituent of ribosome
GO:0003774	motor activity
GO:0003779	actin binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0051015	actin filament binding

Biological Process

GO:0001778	plasma membrane repair
GO:0006412	translation
GO:0008152	metabolic process
GO:0014823	response to activity
GO:0016192	vesicle-mediated transport
GO:0070252	actin-mediated cell contraction

Cellular Component

GO:0005622	intracellular
GO:0005794	Golgi apparatus
GO:0005826	actomyosin contractile ring
GO:0005840	ribosome
GO:0005911	cell-cell junction
GO:0016020	membrane
GO:0016459	myosin complex
GO:0030016	myofibril
GO:0031672	A band
GO:0043234	protein complex