Version 5.4
Bos taurus Gene: DPYSL5
Summary
InnateDB Gene IDBG-636949.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DPYSL5
Gene Name dihydropyrimidinase-related protein 5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018576
Encoded Proteins
IDBP-688931
dihydropyrimidinase-related protein 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157851:
This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:72671399-72760767
Strand Reverse strand
Band
Transcripts
ENSBTAT00000024720 ENSBTAP00000024720
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Biological Process
GO:0006208 pyrimidine nucleobase catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0030425 dendrite
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000157851
View Gene Order
ENSMUSG00000029168
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19199
CRMPs in Sema3A signaling pathway
REACT_111045
Developmental Biology pathway
REACT_19271
Semaphorin interactions pathway
REACT_18266
Axon guidance pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
REACT_263034
Semaphorin interactions pathway
REACT_244852
CRMPs in Sema3A signaling pathway
KEGG
hsa04360
Axon guidance pathway
mmu04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.61842
RefSeq NM_001109964 XM_005212911 XM_005212912 XM_005212913
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca