Version 5.4
Bos taurus Gene: MYHC-EMBRYONIC
Summary
InnateDB Gene IDBG-636957.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYHC-EMBRYONIC
Gene Name myosin-3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011803
Encoded Proteins
IDBP-689018
myosin-3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109063:
Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. This gene is a member of the MYH family and encodes a protein with an IQ domain and a myosin head-like domain. Mutations in this gene have been associated with two congenital contracture (arthrogryposis) syndromes, Freeman-Sheldon syndrome and Sheldon-Hall syndrome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:30230160-30251091
Strand Reverse strand
Band
Transcripts
ENSBTAT00000001120 ENSBTAP00000001120
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000146 microfilament motor activity
GO:0000166 nucleotide binding
GO:0003774 motor activity
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0051015 actin filament binding
Biological Process
GO:0003009 skeletal muscle contraction
GO:0006200 ATP catabolic process
GO:0008152 metabolic process
Cellular Component
GO:0016459 myosin complex
GO:0043292 contractile fiber
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000109063
View Gene Order
ENSMUSG00000020908
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_16969
Striated Muscle Contraction pathway
REACT_17044
Muscle contraction pathway
REACT_11123
Membrane Trafficking pathway
REACT_232053
Striated Muscle Contraction pathway
REACT_262759
Muscle contraction pathway
KEGG
hsa04530
Tight junction pathway
mmu04530
Tight junction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MTZ2 Q8MJU3
UniProt Splice Variant
Entrez Gene 281338
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB090155 DAAA02048849 DAAA02048850
GenPept BAC10417
RNA Seq Atlas 281338

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca