Version 5.4
Bos taurus Gene: IFT80
Summary
InnateDB Gene IDBG-637082.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFT80
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000031572
Encoded Proteins
IDBP-689079
intraflagellar transport 80 homolog (Chlamydomonas)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000068885:
The protein encoded by this gene is part of the intraflagellar transport complex B and is necessary for the function of motile and sensory cilia. Defects in this gene are a cause of asphyxiating thoracic dystrophy 2 (ATD2). Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:107962966-108058677
Strand Forward strand
Band
Transcripts
ENSBTAT00000044761 ENSBTAP00000042227
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0002062 chondrocyte differentiation
GO:0007224 smoothened signaling pathway
GO:0042384 cilium assembly
GO:0045880 positive regulation of smoothened signaling pathway
GO:0050680 negative regulation of epithelial cell proliferation
GO:0060271 cilium morphogenesis
GO:0060349 bone morphogenesis
GO:2000051 negative regulation of non-canonical Wnt signaling pathway
Cellular Component
GO:0005813 centrosome
GO:0005929 cilium
GO:0030992 intraciliary transport particle B
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000068885
View Gene Order
ENSMUSG00000027778
View Gene Order
Cross-References
SwissProt
TrEMBL F1N0G0
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:29262
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02002421 DAAA02002422 DAAA02002423 DAAA02002424 DAAA02002425
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca