InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: DGKZ

Summary

InnateDB Gene

IDBG-637128.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DGKZ

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013636

Encoded Proteins

IDBP-689170

diacylglycerol kinase, zeta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149091:
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:77236630-77248138

Strand

Forward strand

Band

Transcripts

ENSBTAT00000018128

ENSBTAP00000018128

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0001727	lipid kinase activity
GO:0003951	NAD+ kinase activity
GO:0004143	diacylglycerol kinase activity
GO:0004857	enzyme inhibitor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008022	protein C-terminus binding
GO:0016301	kinase activity
GO:0016740	transferase activity

Biological Process

GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008152	metabolic process
GO:0016310	phosphorylation
GO:0031571	mitotic G1 DNA damage checkpoint
GO:0035556	intracellular signal transduction
GO:0043086	negative regulation of catalytic activity
GO:0045930	negative regulation of mitotic cell cycle
GO:0046580	negative regulation of Ras protein signal transduction
GO:0046834	lipid phosphorylation