Version 5.4
Bos taurus Gene: BT.52184
Summary
InnateDB Gene IDBG-637185.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.52184
Gene Name decaprenyl-diphosphate synthase subunit 1
Synonyms COQ1
Species Bos taurus
Ensembl Gene ENSBTAG00000006529
Encoded Proteins
IDBP-689183
decaprenyl-diphosphate synthase subunit 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148459:
The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:18182707-18224123
Strand Reverse strand
Band
Transcripts
ENSBTAT00000008576 ENSBTAP00000008576
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000010 trans-hexaprenyltranstransferase activity
GO:0016740 transferase activity
GO:0046982 protein heterodimerization activity
GO:0050347 trans-octaprenyltranstransferase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0051290 protein heterotetramerization
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000148459
View Gene Order
ENSMUSG00000026784
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160111
Ubiquinol biosynthesis pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_196568
Ubiquinol biosynthesis pathway
KEGG
hsa00900
Terpenoid backbone biosynthesis pathway
mmu00900
Terpenoid backbone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F6RJN8
UniProt Splice Variant
Entrez Gene 509696
UniGene Bt.52184
RefSeq NM_001100331
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02035357 DAAA02035358 DAAA02035359 KC787698
GenPept AGJ84333
RNA Seq Atlas 509696

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca