Bos taurus Gene: BT.62984 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-637328.3 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | BT.62984 | ||||||||||||||||||
Gene Name | melanoma-associated antigen D1 | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||
Ensembl Gene | ENSBTAG00000008733 | ||||||||||||||||||
Encoded Proteins |
melanoma antigen family D, 1
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179222:
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome X:95708020-95714844 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | |||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 74 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
NRAGE signals death through JNK pathway
Role of DCC in regulating apoptosis pathway
Signalling by NGF pathway
p75 NTR receptor-mediated signalling pathway
Apoptosis pathway
Signal Transduction pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
Regulation of Apoptosis pathway
Apoptosis pathway
NRAGE signals death through JNK pathway
Role of DCC in regulating apoptosis pathway
Regulation of Apoptosis pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
Signalling by NGF pathway
Signal Transduction pathway
p75 NTR receptor-mediated signalling pathway
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KEGG |
Neurotrophin signaling pathway pathway
Neurotrophin signaling pathway pathway
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INOH | |||||||||||||||||||
PID NCI |
Neurotrophic factor-mediated Trk receptor signaling
p75(NTR)-mediated signaling
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Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | |||||||||||||||||||
UniGene | Bt.62984 | ||||||||||||||||||
RefSeq | NM_001046125 XM_005228192 XM_005228193 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | |||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||