InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Maged1

Summary

InnateDB Gene

IDBG-160245.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Maged1

Gene Name

melanoma antigen, family D, 1

Synonyms

2810433C11Rik; 5430405L04Rik; Dlixin; Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; mFLJ00163; NRAGE

Species

Mus musculus

Ensembl Gene

ENSMUSG00000025151

Encoded Proteins

IDBP-160249

melanoma antigen, family D, 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179222:
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:94535474-94542143

Strand

Reverse strand

Band

Transcripts

ENSMUST00000026142	ENSMUSP00000026142
ENSMUST00000153386
ENSMUST00000139375
ENSMUST00000138146
ENSMUST00000138731
ENSMUST00000141702
ENSMUST00000133982

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 67 interaction(s) predicted by orthology.

Experimentally validated
Total	23 [view]
Protein-Protein	23 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	67 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003713	transcription coactivator activity
GO:0005515	protein binding

Biological Process

GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0032922	circadian regulation of gene expression
GO:0042752	regulation of circadian rhythm
GO:0043406	positive regulation of MAP kinase activity
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0050680	negative regulation of epithelial cell proliferation
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
GO:2001235	positive regulation of apoptotic signaling pathway