Version 5.4
Bos taurus Gene: NEBL
Summary
InnateDB Gene IDBG-637483.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEBL
Gene Name nebulette
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013339
Encoded Proteins
IDBP-689516
nebulette
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000078114:
This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:22382763-22496405
Strand Reverse strand
Band
Transcripts
ENSBTAT00000061339 ENSBTAP00000053811
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005523 tropomyosin binding
GO:0008092 cytoskeletal protein binding
GO:0031005 filamin binding
GO:0051015 actin filament binding
Biological Process
GO:0071691 cardiac muscle thin filament assembly
Cellular Component
GO:0001725 stress fiber
GO:0030018 Z disc
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000078114
View Gene Order
ENSMUSG00000053702
View Gene Order
Cross-References
SwissProt
TrEMBL F1MF57
UniProt Splice Variant
Entrez Gene 517987
UniGene Bt.15316
RefSeq NM_001191413
HUGO HGNC:16932
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02035408
GenPept
RNA Seq Atlas 517987

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca