Version 5.4
Bos taurus Gene: ULK2
Summary
InnateDB Gene IDBG-637551.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ULK2
Gene Name serine/threonine-protein kinase ULK2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000030977
Encoded Proteins
IDBP-689681
unc-51-like kinase 2
IDBP-689700
unc-51-like kinase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083290:
This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:34405539-34463318
Strand Forward strand
Band
Transcripts
ENSBTAT00000029701 ENSBTAP00000029699
ENSBTAT00000004466 ENSBTAP00000004466
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0000045 autophagic vacuole assembly
GO:0006468 protein phosphorylation
GO:0009103 lipopolysaccharide biosynthetic process
GO:0010506 regulation of autophagy
GO:0042594 response to starvation
GO:0046777 protein autophosphorylation
GO:0048671 negative regulation of collateral sprouting
GO:0048675 axon extension
Cellular Component
GO:0000407 pre-autophagosomal structure
GO:0005829 cytosol
GO:0016020 membrane
GO:0034045 pre-autophagosomal structure membrane
GO:0034273 ATG1/UKL1 signaling complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000083290
View Gene Order
ENSMUSG00000004798
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04150
mTOR signaling pathway pathway
hsa04140
Regulation of autophagy pathway
mmu04140
Regulation of autophagy pathway
mmu04150
mTOR signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.106886
RefSeq NM_001102321 XM_005220405 XM_005220408 XM_005220410
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca