Version 5.4
Bos taurus Gene: NEXN
Summary
InnateDB Gene IDBG-637630.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEXN
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008921
Encoded Proteins
IDBP-689680
nexilin (F actin binding protein)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162614:
This gene encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:66998944-67053966
Strand Reverse strand
Band
Transcripts
ENSBTAT00000039125 ENSBTAP00000038925
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004683 calmodulin-dependent protein kinase activity
GO:0005515 protein binding
GO:0008307 structural constituent of muscle
GO:0051015 actin filament binding
Biological Process
GO:0006468 protein phosphorylation
GO:0030334 regulation of cell migration
GO:0048739 cardiac muscle fiber development
GO:0051493 regulation of cytoskeleton organization
Cellular Component
GO:0030018 Z disc
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000162614
View Gene Order
ENSMUSG00000039103
View Gene Order
Cross-References
SwissProt
TrEMBL E1BDF0
UniProt Splice Variant
Entrez Gene 504819
UniGene
RefSeq XM_003581997 XM_003585886 XM_005204428
HUGO HGNC:29557
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02008247 DAAA02008248
GenPept
RNA Seq Atlas 504819

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca