InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: MSN

Summary

InnateDB Gene

IDBG-637676.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MSN

Gene Name

Moesin

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000003418

Encoded Proteins

IDBP-689703

Moesin

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147065:
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:100070406-100162454

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000017503

ENSBTAP00000017503

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.

Predicted by orthology
Total	44 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003725	double-stranded RNA binding
GO:0003779	actin binding
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0008092	cytoskeletal protein binding
GO:0019901	protein kinase binding
GO:0050839	cell adhesion molecule binding

Biological Process

GO:0007159	leukocyte cell-cell adhesion
GO:0010628	positive regulation of gene expression
GO:0022614	membrane to membrane docking
GO:0050900	leukocyte migration
GO:0061028	establishment of endothelial barrier
GO:2000401	regulation of lymphocyte migration

Cellular Component

GO:0001931	uropod
GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0005902	microvillus
GO:0005925	focal adhesion
GO:0016020	membrane
GO:0016323	basolateral plasma membrane
GO:0016324	apical plasma membrane
GO:0019898	extrinsic component of membrane
GO:0030175	filopodium
GO:0031528	microvillus membrane
GO:0042995	cell projection
GO:0045177	apical part of cell
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle