Version 5.4
Bos taurus Gene: BT.105664
Summary
InnateDB Gene IDBG-637777.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.105664
Gene Name PR domain zinc finger protein 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012999
Encoded Proteins
IDBP-689819
PR domain zinc finger protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110851:
The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:71324566-71347630
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017284 ENSBTAP00000017284
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000110851
View Gene Order
ENSMUSG00000035529
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_13695
p75NTR negatively regulates cell cycle via SC1 pathway
REACT_11061
Signalling by NGF pathway
REACT_13776
p75 NTR receptor-mediated signalling pathway
REACT_111102
Signal Transduction pathway
REACT_248921
Signalling by NGF pathway
REACT_188257
Signal Transduction pathway
REACT_210847
p75 NTR receptor-mediated signalling pathway
REACT_202086
p75NTR negatively regulates cell cycle via SC1 pathway
KEGG
hsa04722
Neurotrophin signaling pathway pathway
mmu04722
Neurotrophin signaling pathway pathway
INOH
PID NCI
p75ntrpathway
p75(NTR)-mediated signaling
Cross-References
SwissProt
TrEMBL E1BDK1
UniProt Splice Variant
Entrez Gene 540731
UniGene Bt.105664 Bt.106223 Bt.108199
RefSeq XM_002687670 XM_005198326 XM_005198327 XM_005206797 XM_005206798 XM_612859
HUGO HGNC:9348
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02013758
GenPept
RNA Seq Atlas 540731

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca