Version 5.4
Bos taurus Gene: HLTF
Summary
InnateDB Gene IDBG-637882.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HLTF
Gene Name helicase-like transcription factor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019704
Encoded Proteins
IDBP-689915
helicase-like transcription factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000071794:
This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:120013765-120075520
Strand Forward strand
Band
Transcripts
ENSBTAT00000034508 ENSBTAP00000034398
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0016887 ATPase activity
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006357 regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000071794
View Gene Order
ENSMUSG00000002428
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_56
Prolactin pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MLM2
UniProt Splice Variant
Entrez Gene 539633
UniGene Bt.103834
RefSeq NM_001192286 XM_005201817 XM_005201818
HUGO HGNC:11099
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02002705 DAAA02002706
GenPept
RNA Seq Atlas 539633

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca