InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CTNND1

Summary

InnateDB Gene

IDBG-637886.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CTNND1

Gene Name

catenin delta-1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002411

Encoded Proteins

IDBP-689916

catenin (cadherin-associated protein), delta 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

InnateDB Annotation from Orthologs

Summary

PMID 25773174

[Mus musculus] Ctnnd1 expressed in alveolar type II epithelial cells plays a critical role in regulating the innate immunity of the entire lung.

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198561:
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:82283934-82329276

Strand

Forward strand

Band

Transcripts

ENSBTAT00000043778

ENSBTAP00000041323

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.

Predicted by orthology
Total	50 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005488	binding
GO:0005515	protein binding
GO:0045296	cadherin binding

Biological Process

GO:0016337	single organismal cell-cell adhesion
GO:0090090	negative regulation of canonical Wnt signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0030496	midbody
GO:0070062	extracellular vesicular exosome