Bos taurus Gene: NMT2
Summary
InnateDB Gene IDBG-638073.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NMT2
Gene Name Glycylpeptide N-tetradecanoyltransferase 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007703
Encoded Proteins
Glycylpeptide N-tetradecanoyltransferase 2
Glycylpeptide N-tetradecanoyltransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152465:
N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases. [provided by RefSeq, Jul 2008]
N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein\'s N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77%% and 96%% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:29967417-30027451
Strand Reverse strand
Band
Transcripts
ENSBTAT00000065061 ENSBTAP00000055459
ENSBTAT00000050460 ENSBTAP00000047156
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006499 N-terminal protein myristoylation
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
The phototransduction cascade pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Disease pathway
Inactivation, recovery and regulation of the phototransduction cascade pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Membrane binding and targetting of GAG proteins pathway
Late Phase of HIV Life Cycle pathway
Synthesis And Processing Of GAG, GAGPOL Polyproteins pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
HIV Life Cycle pathway
Visual phototransduction pathway
HIV Infection pathway
The phototransduction cascade pathway
Inactivation, recovery and regulation of the phototransduction cascade pathway
Assembly Of The HIV Virion pathway
Disease pathway
Disease pathway
Visual phototransduction pathway
Inactivation, recovery and regulation of the phototransduction cascade pathway
The phototransduction cascade pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9N181
TrEMBL G3N0U1 Q9GL39
UniProt Splice Variant
Entrez Gene 282049
UniGene Bt.249
RefSeq NM_174456 XM_005193342
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF222687 AY007993 DAAA02035539 DAAA02035540
GenPept AAF31456 AAG16636
RNA Seq Atlas 282049